Eczema and psoriasis are common non-contagious skin disorders.
Eczema, medically called "atopic dermatitis" is a
chronic, inflammatory skin disorder that affects more than 35
million people in the United States. This skin disorder often times
occurs in people who suffer from asthma and hay fever. Symptoms of
eczema are skin swelling, itching, inflammation, and eventually
scaling and cracking. The prevalence of eczema is mostly found in
children less than 18 years old who make up 80% of reported
incidences. People who suffer with eczema commonly experience
periods when the skin disorder is worse called exacerbations or
flares, followed by periods when the skin improves or clears up
entirely, called remissions. Most of the children who have eczema
will realize a temporary remission from the disorder generally when
they reach age of 18 to 21 years, although their skin often remains
dry and easily irritated.
Psoriasis is a chronic skin disorder marked by periodic flare-ups
of sharply defined red patches covered by a crusty, flaky surface.
It is estimated that there are 9 million people in the U.S. that
suffer with psoriasis. It is generally believed that psoriasis is a
disorder in which factors in the immune system, enzymes, and other
biochemical substances that regulate skin-cell division become
impaired resulting in rapid keratinocyte (immature skin cell)
proliferation and inflammation. It is believed that such
abnormalities in skin growth are likely due to one or more genetic
defects and that environmental triggers such as weather or stress
play a factor in the onset of the disorder.
The current consensus in the scientific community is that
exacerbated immune response episodes play an important role in skin
disorders such as eczema and psoriasis. During normal immune
response against infection the human body significantly increases
the level of lymphocytes and cytokine cells used to eliminate
microorganism and toxins. Lymphocytes and cytokine cells release
enzymes and proteases as well as recruit phagocyte cells that
release a delicate balance of hydrogen peroxide, hydroxide ion
radical, and super-oxygen anion radical as bio-physiological
weapons to eliminate infections, allergens, and toxins. When
infections have been subdued lymphocyte and cytokine production
return to normal levels. Yet, when some people are challenged with
microorganisms (e.g., bacteria), fungi, yeast, and allergens
(chemicals, pollen) their immune response is highly exacerbated, a
dysfunctional physiological event that leads to severe
inflammation, itching, dryness, and damaged skin. It is currently
accepted that inherited genetic factors are the major causes for
this dysfunction in the immune response mechanism. However, this
dysfunction in immune response may very well be traced back to a
malfunction in the signal expression from released prostaglandins
during the onset of the inflammation process.
Current Treatments Approaches Fall Short
Itching and dry cracking skin are not the causes of eczema or
psoriasis but are merely symptoms of more complex underlying
physiological events. Exacerbated immune episodes probably are the
results of one or more prostaglandin signal malfunctions that occur
when eczema suffers are challenged with microbiological, toxins,
and allergen intrusions into the human body. Prostaglandin releases
are controlled by the body's production of cytokines, which are
released by circulating leukocytes during infectious events.
Prostaglandins are responsible for the production of special
organic acids, which regulate the inflammation process during the
human immune response mechanism. Prostaglandins are also involved
in the recruitment of phagocyte cells that help assist in the
elimination of bacteria and other foreign substances. However,
during infectious events some individuals will exhibit exacerbated
immune responses, which probably can be linked to prostaglandin
malfunctions during the immune response.
This prostaglandin malfunction ultimately leads to chronic
inflammation, itching, and skin damage. Further damage to skin
tissue is the result of a continuing build up of neutrophils
(phagocytes) at the site of infection or intrusion, which continue
to release high concentration levels of proteases and oxidizing
agents such as hydrogen peroxide, hydroxyl radical anion, and
super-oxygen radical anion that kill not only bacteria, yeast, or
fungus but results in severely damaged dry skin. The end result of
these exacerbated immune responses is damage to surrounding skin
tissue(dry, cracking) and eventual scarring. Thus, only using
so-called natural oils, pharmaceutical moisturizers, or synthetic
cortisones to relive the type of itching and cracking skin observed
in eczema and psoriasis suffers can only have a mediocre and
temporary effect.
Natural Scientific Approaches Needed
Natural scientific solutions should be researched and developed
that will help minimizing exacerbated immune responses in
individuals battling with eczema and psoriasis. Such product
solutions should exhibit very little to no human toxicity, have no
adverse skin reactivity (statistically no different than control
populations), and the long-term use should not result in
deleterious human side effects. New emerging scientific research is
showing that extracts from various plant, fruit, and flowers may
prove to be useful in the search for safe and effective
alternatives to the use of steroids and dangerous skin creams.
Eczema and Psoriasis: The Natural Scientific Approach
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